| "Broken, Beat & Scarred", "Cyanide", and "My Apocalypse" | Beat "The Thing That Should Not Be" on any career mode |
| James Hetfield | Get 100 stars on Vocals Career Mode |
| James Hetfield Classic | Get 150 stars on Vocals Career Mode |
| James Hetfield ZOMBIE | Earn 200 stars in Vocal Career |
| King Diamond | Play "Evil" on any career mode |
| Kirk Hammett | Get 100 stars on Guitar Career Mode |
| Kirk Hammett Classic | Get 150 stars on Guitar Career Mode |
| Kirk Hammett ZOMBIE | Earn 200 stars in Guitar Career |
| Klown Bass | Earn 45 stars in Bass Career |
| Lars Ulrich | Get 100 stars on Drums Career Mode |
| Lars Ulrich Classic | Earn 150 stars in Drums Career |
| Lars Ulrich ZOMBIE | Earn 200 stars in Drums Career |
| Lemmy | Play "Ace Of Spades" on any career mode |
| Mean Green Bass | Earn 25 stars in Bass Career |
| Rob Trujillo Classic | Earn 150 stars in Bass Career |
| Rob Trujillo ZOMBIE | Earn 200 stars in Bass Career |
| Robert Trujillo | Get 100 stars on Bass Career Mode |
| Shirley Crowley | Earn 55 stars in Bass Career |
| Zach Harmon | Earn 100 stars in Band Career |
| Zach Harmon (Alt) | Earn 100 stars in Band Career |
